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LS mean reductions from baseline were 8.6 to 11.4 mm Hg for diastolic BP and 10.6 to 12.2 mm Hg for systolic BP, compared with placebo. In addition, the nebivolol patients who received doses of 5 mg or more had significantly greater LS mean reductions in trough diastolic BP (7.7–8.3 mm Hg) compared with placebo patients. This medication works by blocking the action of certain natural substances in buy bystolic 10 mg online your body, such as epinephrine, on the heart and blood vessels. It lowers the blood pressure which may lower the risk of a stroke or heart attack. Health Canada evaluates every Canadian generic for their safety, effectiveness, and quality. Every generic used in Canada has the same medical ingredients as their brand name counterpart and is considered bioequivalent to the brand name medication.